Tue 11 Jun 09:30: Child Development Forum Easter II
Abigail Agyemang (Psychology/Education) – Mathematics Anxiety in Underrepresented Secondary School Children
Irena Tetkovic (Psychiatry) – SIBWELL : Supporting siblings of children and young people with mental health conditions in their wellbeing
Keith Liang (Psychology) – Rhythm in Speech, rhythm in brain, and learning to read in adolescence in East Asia
Child Development Forum are a series of talks bringing together researchers of infant, child and adolescent development across the University of Cambridge.
Talks are termly, and usually held at the MRC Cognition and Brain Sciences Unit (Chaucer Road).
Join the mailing list to kept up-to-date, and sign up to give a talk:
https://lists.cam.ac.uk/sympa/info/ucam-childdevforum
This talk is part of the Child Development Forum (CDF) series.
- Speaker: Abigail Agyemang (Psychology), Irena Tetkovic (Psychiatry), Keith Liang (Psychology)
- Tuesday 11 June 2024, 09:30-11:00
- Venue: Old Cavendish Psychology Ground Floor Seminar Room.
- Series: Child Development Forum (CDF); organiser: Giacomo.
Tue 14 May 12:00: Title to be confirmed
Abstract not available
- Speaker: Prof Ruth Itzhaki
- Tuesday 14 May 2024, 12:00-13:00
- Venue: Seminar Room, John van Geest Centre for Brain Repair, Forvie Site.
- Series: Clinical Neurosciences Seminars; organiser: Louise Massara.
Thu 09 May 12:00: “Protecting and regenerating the diseased nervous system: Lessons from development” The talk is in-person only and a recording is not available.
Abstract not available
The talk is in-person only and a recording is not available.
- Speaker: Prof Michel Cayouette, Montreal Clinical Research Institute (IRCM)
- Thursday 09 May 2024, 12:00-13:00
- Venue: Seminar Room, John van Geest Centre for Brain Repair, Forvie Site.
- Series: Clinical Neurosciences Seminars; organiser: Louise Massara.
Thu 23 May 16:00: How innate immune cells adapt to environment and function: diverse tales of mitochondria
Innate immune cells, such as macrophages and dendritic cells, inhabit all body organs to detect danger and initiate immune responses as well as to maintain organ health. However, the mechanisms facilitating those diverse functions of innate immune cells in distinct tissue milieus are poorly understood.
Recently, we found tissue macrophages to engage their mitochondrial metabolism in an organ-specific manner. Mechanistically, they adapt the activity of their mitochondrial electron transport chain to handle large amounts of environmental lipids in homeostasis. This functional dependence of tissue macrophages on mitochondrial metabolism can be harnessed to ameliorate obesity-related pathologies. On the other hand, innate immune cells have to quickly respond to insults and activate immunity for containment, in particular conventional dendritic cells. We discovered a differential bioenergetic dependence of the immunogenic responsiveness of type 1 versus type 2 dendritic cells (unpublished data). The distinct engagement of mitochondrial metabolism regulates the epigenetic state and functional outputs of dendritic cell subsets and affects their potency to induce anti-cancer immunity.
Overall, my talk will focus on how mitochondria and an active electron transport chain regulate the context-dependent functions of innate immune cells via entirely distinct molecular mechanisms.
- Speaker: Stefanie Wculek, IRB (Biomedical Research Institute, Barcelona)
- Thursday 23 May 2024, 16:00-17:00
- Venue: Hodgkin Huxley Seminar Room, Physiology builiding, Downing Site CB2 3EG.
- Series: Foster Talks; organiser: er454.
Wed 01 May 15:00: Behavioural Science and Security: Informing Evidence-based Policy and Practice
This talk will give an overview of how and why risk perception and communication are important by sharing collaborative work, discussing some of the UK systems and Behavioural and Social Science policy advice.
- Speaker: Brooke Rogers (King's College London)
- Wednesday 01 May 2024, 15:00-16:00
- Venue: Ground Floor Lecture Theatre, Department of Psychology, Downing Site, Cambridge.
- Series: Social Psychology Seminar Series (SPSS); organiser: Yara Kyrychenko.
Mon 15 Jul 12:30: Therapeutic ultrasound for brain therapy
Abstract: TBC
Bio: Dr Sophie Morse is a European Talent Academy Fellow and an Emerging Leader in the Dementia Research Institute at Imperial College. During her PhD, she developed innovative methods to enhance drug delivery to the brain using focused ultrasound and microbubbles. Currently, Dr Morse leads a research group investigating how focused ultrasound can non-invasively stimulate cells in our brain, particularly glial cells and immune cells, to find new ways of treating Alzheimer’s disease, brain tumours and even slow down ageing.
Venue: MRC CBU West Wing Seminar Room and Zoom https://us02web.zoom.us/j/82385113580?pwd=RmxIUmphQW9Ud1JBby9nTDQzR0NRdz09
- Speaker: Sophie Morse (Imperial College London)
- Monday 15 July 2024, 12:30-13:30
- Venue: MRC-CBU, 15 Chaucer Road, Cambridge.
- Series: CBU Monday Methods Meeting; organiser: Dace Apšvalka.
Mon 08 Jul 12:30: TBC
Abstract: TBC
Bio: Stefan Haufe is a professor of computer science and head of the UNIML (Uncertainty, Inverse Modeling and Machine Learning) group at the Technical University of Berlin. His research focuses on developing and validating signal processing, inverse modelling and machine-learning techniques for neuroimaging and other medical data.
Venue: MRC CBU West Wing Seminar Room and Zoom https://us02web.zoom.us/j/82385113580?pwd=RmxIUmphQW9Ud1JBby9nTDQzR0NRdz09
- Speaker: Stefan Haufe (Technical University of Berlin)
- Monday 08 July 2024, 12:30-13:30
- Venue: MRC-CBU, 15 Chaucer Road, Cambridge.
- Series: CBU Monday Methods Meeting; organiser: Dace Apšvalka.
Thu 09 May 14:00: Learning and memory in developmental amnesia
Abstract not available
- Speaker: Rachael Elward (London South Bank University)
- Thursday 09 May 2024, 14:00-15:00
- Venue: MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge - Lecture Theatre.
- Series: Chaucer Club; organiser: Vicky Collins.
Wed 08 May 12:15: Unifying the mechanisms of the hippocampal and prefrontal cognitive maps
Cognitive maps have emerged as leading candidates, both conceptually and neurally, for explaining how brains seamlessly generalize structured knowledge across apparently different scenarios. Two brain systems are implicated in cognitive mapping: the hippocampal formation and the prefrontal cortex. Neural activity in these brain regions, however, differs during the same task, indicating that the regions have different mechanisms for cognitive mapping. In this talk, we first provide a mechanistic understanding of how the hippocampal and prefrontal systems could build cognitive maps (with the hippocampal mechanism related to transformers and the prefrontal mechanism related to RNNs/SSMs); second, we demonstrate how these two mechanisms explain a wealth of neural data in both brain regions; and lastly, we prove that the two different mechanisms are, in fact, mathematically equivalent.
- Speaker: James Whittington, Sir Henry Wellcome Postdoctoral Fellow, Stanford University & Oxford University
- Wednesday 08 May 2024, 12:15-13:15
- Venue: CBL Seminar Room, Engineering Department, 4th floor Baker building.
- Series: Computational Neuroscience; organiser: Samuel Eckmann.
Wed 01 May 14:00: Computational Neuroscience Journal Club
Please join us for our Computational Neuroscience journal club on Wednesday 1st May at 2pm UK time in the CBL seminar room
The title is “Feedback Controllability is a Normative Theory of Neural Population Dynamics”, presented by Rui Xia and Youjing Yu.
Summary:
In the production of complex behaviors such as locating, identifying, and grasping food, the brain employs feedback mechanisms, wherein the outputs of a system are rerouted as inputs. Despite substantial evidence supporting feedback control as a normative theory of behavior, if and how feedback control explains neural population dynamics has been largely unarticulated.
In this journal club, we will explore the concept of feedback controllability as a normative theory for understanding neural population dynamics [1]. We will first introduce foundational mathematical concepts of control theory, including controllability, feedback controllers, particularly the Linear Quadratic Regulator. Subsequently, we will discuss the novel dimensionality reduction methods designed to identify subspaces within neural population data that are most feed-forward controllable (FFC) vs. feedback controllable (FBC). Experimental results are then presented to show FBC subspaces as better decoders of behavior and how these two subspaces carry distinct computations with differing regimes of emergent dynamics.
[1] Bouchard, Kristofer, and Ankit Kumar. “Feedback Controllability is a Normative Theory of Neural Population Dynamics.” (2024)
- Speaker: Rui Xia, Youjing Yu
- Wednesday 01 May 2024, 14:00-16:00
- Venue: CBL Seminar Room, Engineering Department, 4th floor Baker building.
- Series: Computational Neuroscience; organiser: Puria Radmard.
Thu 02 May 12:00: “On Brains and Vessels: How perivascular fibroblasts contribute to ALS neurodegeneration” In person only. (No recording will be available.)
Abstract not available
In person only. (No recording will be available.)
- Speaker: Sebastian Lewandowski, Karolinska Institutet
- Thursday 02 May 2024, 12:00-13:00
- Venue: Seminar Room, John van Geest Centre for Brain Repair, Forvie Site.
- Series: Clinical Neurosciences Seminars; organiser: Louise Massara.
Mon 29 Apr 16:15: Egocentric and allocentric representations in cortical structures
Abstract not available
- Speaker: Michael Hasselmo, Boston University, Massachusetts, U.S.A.
- Monday 29 April 2024, 16:15-18:00
- Venue: Hodgkin-Huxley Seminar Room.
- Series: Adrian Seminars in Neuroscience; organiser: jk727.
Thu 25 Apr 16:00: Eating and Walking - how cells manage their energy budget during migration and invasion
Abstract not available
- Speaker: Laura Machesky, Department of Biochemistry, University of Cambridge
- Thursday 25 April 2024, 16:00-17:00
- Venue: Hodgkin Huxley Seminar Room, Physiology builiding, Downing Site CB2 3EG.
- Series: Foster Talks; organiser: er454.
Wed 01 May 11:30: Perceptual decision-making in autism: From neurochemistry to cognition
Our brains evaluate sensory information from the environment and use it to guide behaviour. This shapes how we interact with the world and ultimately, our physical and mental well-being. Understanding the mechanisms of perceptual decision-making is of relevance for neurodiverse populations such as autistic individuals. Here I present findings from experimental psychology, computational modelling, and brain imaging (including ultra-high-resolution Magnetic Resonance Spectroscopy) that show a) the behavioural similarities and differences between autistic and non-autistic adults during perceptual decision-making, and b) the relationships between neurotransmitters, autistic traits, and perceptual choice in adults. By integrating novel computational modelling approaches with classic task paradigms, this line of research helps bridge the gaps between neurochemistry and cognition and offers new insights into the cognitive neuroscience of autism.
- Speaker: Nazia Jassim, University of Cambridge
- Wednesday 01 May 2024, 11:30-12:30
- Venue: https://us02web.zoom.us/j/81268825017?pwd=dndNSE9selNDTktIUGNNejZKZDFVUT09 .
- Series: ARClub Talks; organiser: Simon Braschi.
Fri 10 May 13:00: Multi-tissue tectonics enable self-assembly of the vertebrate body axis
Abstract not available
- Speaker: Benjamin Steventon, Department of Genetics
- Friday 10 May 2024, 13:00-14:00
- Venue: Biffen Theater- Please subscribe to mailing list for link.
- Series: Developmental Biology Seminar Series; organiser: Theresa Gross-Thebing.
Fri 03 May 13:00: An ancient regulatory network sets the position of the forebrain in chordates
Abstract not available
- Speaker: Elia Benito-Gutierrez, Department of Zoology/Genentech
- Friday 03 May 2024, 13:00-14:00
- Venue: Biffen Theater- Please subscribe to mailing list for link.
- Series: Developmental Biology Seminar Series; organiser: Theresa Gross-Thebing.
Fri 26 Apr 13:00: Differential tissue deformability underlies fluid pressure driven shape divergence of the embryonic brain and spinal cord
Abstract not available
- Speaker: Susannah McLaren, Gurdon Institute
- Friday 26 April 2024, 13:00-14:00
- Venue: Biffen Theater- Please subscribe to mailing list for link.
- Series: Developmental Biology Seminar Series; organiser: Theresa Gross-Thebing.
Wed 01 May 11:30: Perceptual decision-making in autism: From neurochemistry to cognition
Our brains evaluate sensory information from the environment and using it to guide behaviour. This shapes how we interact with the world and ultimately, our physical and mental well-being. Understanding the mechanisms of perceptual decision-making is of relevance for neurodiverse populations such as autistic individuals. Here I present findings from experimental psychology, computational modelling, and brain imaging (including ultra-high-resolution Magnetic Resonance Spectroscopy) that show a) the behavioural similarities and differences between autistic and non-autistic adults during perceptual decision-making, and b) the relationships between neurotransmitters, autistic traits, and perceptual choice in adults. By integrating novel computational modelling approaches with classic task paradigms, this line of research helps bridge the gaps between neurochemistry and cognition and offers new insights into the cognitive neuroscience of autism.
- Speaker: Nazia Jassim, University of Cambridge
- Wednesday 01 May 2024, 11:30-12:30
- Venue: https://us02web.zoom.us/j/81268825017?pwd=dndNSE9selNDTktIUGNNejZKZDFVUT09 .
- Series: ARClub Talks; organiser: Simon Braschi.
Thu 02 May 12:00: Title to be confirmed
Abstract not available
- Speaker: Sebastian Lewandowski, Karolinska Institutet
- Thursday 02 May 2024, 12:00-13:00
- Venue: Seminar Room, John van Geest Centre for Brain Repair, Forvie Site.
- Series: Clinical Neurosciences Seminars; organiser: Louise Massara.
Mon 17 Jun 12:30: FSL-MRS as an alternative to MRspa for 1H MRS processing
Abstract: TBC
Venue: MRC CBU West Wing Seminar Room and Zoom https://us02web.zoom.us/j/82385113580?pwd=RmxIUmphQW9Ud1JBby9nTDQzR0NRdz09
- Speaker: Speaker to be confirmed
- Monday 17 June 2024, 12:30-13:30
- Venue: MRC-CBU, 15 Chaucer Road, Cambridge.
- Series: CBU Monday Methods Meeting; organiser: Dace Apšvalka.