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Schizophrenic individuals suffer from psychosis, that is, hallucinations and delusions that can be very intense and debilitating. Current anti-psychotics do quite a good job suppressing these psychotic symptoms. However they do not do very much to address the cognitive symptoms, and so the cognitive symptoms – impairments in learning, memory, perception, reasoning, etc – persist. Thus, “Antipsychotic drugs have emptied out our mental institutions, but have delivered their residents to impoverished lives outside. Research has linked elements of this poor psychosocial function to persistent cognitive impairments.” (Geyer & Tamminga, 2004). We work on the development of assays for understanding cognition in models of schizophrenia. We are members of the NEWMEDS consortium, which is part of the European Union Innovative Medicines Initiative. NEWMEDS brings together scientists from academic institutions with a wide range of expertise, as well as most of the major European biopharmaceutical companies. The project focuses on developing new animal models and the use of brain recording and behavioural tests to identify innovative and effective drugs for schizophrenia.


Dr Johan   Alsio
My main research interest is the cognitive control over behaviour in health and disease. I am currently studying the neurobiological basis of cognitive flexibility in the intact brain and in preclinical models of schizophrenia.
Professor Tim  Bussey
Professor of Behavioural Neuroscience
Fellow of Pembroke College
+44 (0)1223 333585
 Daniel  Kofink
Visiting MSc student from Utrecht University, September 2011 - May 2012.
Research Associate 2010-2012. Now at Nature.
Dr Adam  Mar
Working on the development and validation of a cognitive test battery for schizophrenia as part of the NEWMEDS project.
 Katie  McAllister
PhD student 2008-2012. Development and validation of preclinical touchscreen tasks for the assessment of cognitive impairments present in schizophrenia. Now at The Boston Consulting Group (London Office).
Dr Charlotte  Oomen
I am very interested in how learning and memory processes change in conditions of psychopathology such as schizophrenia and stress. My research focusses on the neurobiology and anatomy underlying paired associate learning (PAL), and spatial working memory
Professor Lisa  Saksida
Professor of Cognitive Neuroscience
Fellow of Newnham College
+44 (0)1223 765207
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Cambridge Memory Meeting 2015

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